Sigal Miyara Brown Ph.D.
A researcher
- Institute of Plant Protection
- Entomology and Units for Nematology and Chemistry
- Dept. of Entomology and units of Nematology and Chemistry ARO, Volcani Center HaMaccabim Road 68 P.
- +972-506220084
- +972-39603353
Biography
My name is Sigal Braun and I was born in Moshav Yad Natan, in Lachish region,
My academic studies started with a Bachelor’s degree from the Faculty of Agriculture, a Master’s degree in Plant Sciences from Tel Aviv University, and a PhD focused on understanding the pathogenicity of the fungus Colletotrichum acutatum on strawberries, under the supervision of Dr. Stanley Freeman and Professor Oded Yarden.
After completing my PhD, I traveled for a postdoctoral fellowship in Madison, Wisconsin, in Professor Nancy Keller’s lab, where I researched Aspergillus flavus and the genetic factors leading to the production of toxins and secondary metabolites.
Since 2010, I have been leading research in the Department of Entomology, focusing on plant-nematode interactions with the aim of understanding the ongoing dynamics between plants and nematodes. I believe that studying this relationship will reveal key points crucial to understanding the observed pathogenicity. Plant-parasitic nematodes represent a complex world; as part of the nematode system, they are among the most biologically diverse systems.
In our lab, we value maintaining continuous connections with advisors, regional agricultural research and development centers, regional agricultural extension agents and farmers, which provides us with essential field connections and insights into emerging nematological issues. Together, we work on developing sustainable management strategies to address the problem of plant-parasitic nematodes in agriculture.
Research Interests
In the agricultural world, plant-parasitic nematodes pose a severe threat to crop yields and the economic potential of farmers. The damage they cause can be substantial, yet farmers are often unaware of the significant reduction in yield caused by nematodes, which complicates the diagnosis and prevention of extensive damage. The nematicide and disinfectant market, in turn, is highly dynamic and sensitive, governed by stringent regulations aimed at reducing the use of harmful substances for human health and environmental reasons. This trend is leading to a shift towards substances with narrower activity ranges, requiring adjustments to nematode control strategies.
At our laboratory, located at the Volcani Institute in the Department of Entomology and the Nematology and Chemistry Units, we engage in applied and fundamental research aimed at developing environmentally sustainable nematode control strategies. In applied research, we focus on creating tailored control measures by gaining a deep understanding of the soil’s ecological complex. We recognize that laboratory research on a single pathogen does not always reflect real-field conditions; thus, we strive to understand the full complexity of the disease, including all its components and their overall effects. This knowledge enables us to develop more precise and effective control methods.
Additionally, we investigate the impact of global warming on nematode damage. Funded by the Chief Scientist’s Fund of the Ministry of Agriculture, our recent research has shown that nematodes such as Meloidogyne spp and Pratylenchus capsici, which cause significant damage globally and locally, exhibit higher reproduction rates at elevated temperatures. This data necessitates the adaptation of our control measures to changing conditions to ensure optimal yield and productivity.
In our fundamental research, we delve into the role of “effector” proteins secreted by nematodes from their glandular cells during infection. These proteins are crucial for establishing feeding cells within the host, helping nematodes evade programmed cell death and manipulate plant defense mechanisms. A deep understanding of these processes will allow us to develop new strategies to combat nematodes.
Furthermore, we are advancing business collaborations and innovative projects, such as developing biological control agents based on predatory nematodes that feed on parasitic nematodes and creating nematode-trapping films. Our goal is to develop sustainable products that offer innovative and effective solutions for nematode management while protecting the environment and human health.