Our ExAgBov (Exom Agragate of Bovine) database, is the first public database of annotated variations from deep sequencing obtained from hundreds of bovine whole-exome sequencing samples

Link to the paper

Link to the database 

Publications:

Weller, J. I., Gershoni, M., & Ezra, E. (2022). Breeding Dairy Cattle for Female Fertility and Production in the Age of Genomics. Veterinary Sciences, 9(8), 434.‏

Raz, R., Roth, Z. & Gershoni, M. (2022), ExAgBov: A public database of annotated variations from hundreds of bovine whole-exome sequencing samples. Sci Data 9, 469 . 

Weller JI, Ezra E, Gershoni M. (2022), Genetic and genomic analysis of age at first insemination in Israeli dairy cattle. J Dairy Sci. 

Gershoni M, Shirak A, Raz R, Seroussi E., (2022) Comparing BeadChip and WGS Genotyping: Non-Technical Failed Calling Is Attributable to Additional Variation within the Probe Target Sequence., Genes. 9;13(3):485. 

Weller, J.I., Ezra, E. & Gershoni, M*. (2021) Broad phenotypic impact of the effects of transgenerational heat stress in dairy cattle: a study of four consecutive generations. Genet Sel Evol 53, 69 

Arafat M, Kleiman SE, AbuMadighem A, Zeadna A, Levitas E, Vardi IH, Barda S, Lehavi O, Hauser R, Lunenfeld E, Huleihel M, Gershoni M**, Parvari R.(2021). Pathogenic variations in Germ Cell Nuclear Acidic Peptidase (GCNA) are associated with human male infertility. European Journal of Human Genetics

Gershoni, M., Weller, J. I., & Ezra, E. (2021). Genetic and Genome-Wide Association Analysis of Yearling Weight Gain in Israel Holstein Dairy Calves. Genes, 12(5), 708.‏

Weller, J. I., Gershoni, M., & Ezra, E. (2021)., Genetic and environmental analysis of female calf survival in the Israel Holstein cattle population. Journal of Dairy Science

Foreman M, Gershoni M, Barkan D. (2020)., A Simplified and Efficient Method for Himar-1 Transposon Sequencing in Bacteria, Demonstrated by Creation and Analysis of a Saturated Transposon-Mutant Library in Mycobacterium abscessus. mSystems. 

Arafat, M., Harlev, A., Har-Vardi, I., Levitas, E., Priel, T., Gershoni, M., Searby, C., Sheffield, V. C., Lunenfeld, E., & Parvari, R. Mutation in CATIP (C2orf62) causes oligoteratoasthenozoospermia by affecting actin dynamics. Journal of medical genetics, 2020

Gershoni, M., Ezra, E., & Weller, J. I. Genetic and genomic analysis of long insemination interval in Israeli dairy cattle as an indicator of early abortions. Journal of Dairy Science, 2020.‏

Seroussi E, Shirak A, Gershoni M, Ezra E, de Abreu Santos DJ, Ma L, Liu GE. Bos taurus-indicus hybridization correlates with intralocus sexual-conflict effects of PRDM9 on male and female fertility in Holstein cattle. BMC Genet. 2019 

Gershoni M, Hauser R., Barda S., Lehavi O., Arama E., Pietrokovski S., & Kleiman S. E. A new MEIOB mutation is a recurrent cause for azoospermia and testicular meiotic arrest. Human Reproduction. 2019.

Nuta GC, Gilad Y, Gershoni M, Sznajderman A, Schlesinger T, Bialik S, Eisenstein M, Pietrokovski S, Kimchi A. A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation. Autophagy. 2019

Gershoni M, Hauser R, Yogev L, Lehavi O, Azem F, Yavetz H, Pietrokovski S, Kleiman SE. A familial study of azoospermic men identifies three novel causative mutations in three new human azoospermia genes. Genet Med. 2017 

Gershoni M*, Pietrokovski S. The landscape of sex-differential transcriptome and its consequent selection in human adults. BMC Biol. 2017 

Rappaport N, Twik M, Plaschkes I, Nudel R, Iny Stein T, Levitt J, Gershoni M, Morrey CP, Safran M, Lancet D. MalaCards: an amalgamated human disease compendium with diverse clinical and genetic annotation and structured search. Nucleic Acids Res. 2017  

Riemersma M, Mandel H, van Beusekom E, Gazzoli I, Roscioli T, Eran A, Gershoni-Baruch R, Gershoni M, Pietrokovski S, Vissers LE, Lefeber DJ, Willemsen MA, Wevers RA, van Bokhoven H. Absence of α- and β dystroglycan is associated with Walker-Warburg syndrome. Neurology. 2015 

Gershoni M, Levin L, Ovadia O, Toiw Y, Shani N, Dadon S, Barzilai N, Bergman A, Atzmon G, Wainstein J, Tsur A, Nijtmans L, Glaser B, Mishmar D. Disrupting mitochondrial-nuclear coevolution affects OXPHOS complex I integrity and impacts human health. Genome Biol Evol. 2014 

Gershoni M, Pietrokovski S. Reduced selection and accumulation of deleterious mutations in genes exclusively expressed in men. Nat Commun. 2014 

Gershoni M, Fuchs A, Shani N, Fridman Y, Corral-Debrinski M, Aharoni A, Frishman D, Mishmar D. Coevolution predicts direct interactions between mtDNA-encoded and nDNA-encoded subunits of oxidative phosphorylation complex I. J Mol Biol. 2010

Gershoni M, Templeton AR, Mishmar D. Mitochondrial bioenergetics as a major motive force of speciation. Bioessays. 2009 

Mishmar D, Gershoni M. Treating speciation processes as complex traits. Nature Reviews Genetics 8, 320 2007).

*Corresponding authors **co-last author