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About Institutes Public Relations Technology Transfer Students\International Library Administration
שלח באימייל הדפס
Name: Arye (Arik) Harel, Ph.D. (Researcher)
Units: Plant SciencesVegetable and Field Crops
Research Interests / Job description  Latest Chapters In Blog
Tel:  972-3-9683644
Cell: 972-50-6220548
Email:  aryeharel@volcani.agri.gov.il  harelarik@gmail.com
Office location:Room 101, Crop Science building.
Address:Institute of Plant Sciences, ARO Volcani, HaMaccabim Road, P.O.B 15159 Rishon LeZion 7528809, ISRAEL

Research Interests / Job description
Biotic stress research:

* Studying the genetic base of plant microbe interactions. Focus on tomato-Botrytis cinerea system.

* Evolutionary forces that shape the genomes of microbial phytopathogens (fungi, and bacteria).

* Molecular mechanisms of plant defense.
Current Lab members:
  • Eswari Pandaranayaka P.J, Postdoc. Deciphering pathogenicity mechanisms of phytopathogenic fungi and oomycetes using protein network analysis.
  • Yonatan Maayan, Technician (BSc). Computational analysis of the genetic base of resistance-breaking in Tobamoviruses.
  • Nimrod Tish, Undergarduate student.Identifying B. cinerea resistant tomato lines.
  • Dhruv Srivastava, Postdoc. Deciphering pathogenicity mechanisms of phytopathogenic fungi and oomycetes using molecular approach. 
  • Ekaterina Manasherova. Lab Technician (PhD).


Former lab members:

  • Reut feldbaum, Undergraduate. Characterization of B. cinerea associated Phyllosphere.
  • Asaf Cohen,  Undergraduate. Trait prediction of bacteria utilizing deep learning (machine learning)
  • Mariana Mor (2015-16), Diversity of B. cinerea isolates.
  • Hagit Shoyhet (2016), Undergarduate student. Diversity of B. cinerea isolates.
  • Galia Appel (2015), Identification of pathogenic determinants in fungal phytopathogens.


Srivastava DA., Mor M., Feldbaum R., Tish N.,  Shoyhet H., Manasherova E.,  Pandaranayaka E.,  Rav-David D .,  Elad Y., Harel A. (2018) Multivariate analysis of diversity in Botrytis cinerea isolates from Israel. Phytoparasitica. Submitted.

Maayan Y., Pandaranayaka E., Srivastava DA., Lapidot M., Levin I., Dombrovsky A., Harel A. (2018) Using genomic analysis to identify tomato Tm-2 resistance breaking mutations and their underlined evolutionary path in a new and emerging tobamovirus. Archives of Virology. Accepted.

Harel A, Häggblom M, Falkowski PG, and Yee N.
(2016). E
volution of prokaryotic respiratory molybdoenzymes and the frequency of their genomic co-occurrence. FEMS Microbiology Ecology 10.1093/femsec/fiw187.

Harel A, Karkar S, Falkowski P, and Bhattacharya D. (2015). Deciphering primordial cyanobacterial genome functions from network analysis of proteins. Current Biology. 25(5):628-34.

Yee N, Choi J, Porter A, Carey S, Rauschenbach I, Harel A. (2014). Selenate reductase activity requires Isc iron-sulfur cluster biosynthesis genes. FEMS Microbiology Letters. 361:138–143.

Harel A
, Bromberg Y, Falkowski P, and Bhattacharya D. (2013). The evolutionary history of redox metal-binding domains across the tree of life. Proc Natl Acad Sci USA. 111:7042-47.

Kim JD, Senn S, Harel A, Jelen BI, Falkowski PG. (2013). Discovering the electronic circuit diagram of life: structural relationships among transition metal binding sites in oxidoreductases. Philos Trans R Soc Lond B Biol Sci. 368(1622):20120257-66. Review article.

Harel A, Falkowski P, Bromberg Y. (2012). TrAnsFuSE refines the search for protein function: oxidoreductases. Integr Biol (Camb) 4(7):765-77.

Harel A
, Dalah I, Pietrokovski M, Safran M and Lancet D. Omics Data Management and Annotation, Chapter 3 Bioinformatics for Omics Data: Methods and Protocols Series: Methods in Molecular Biology, Vol. 719, ISBN: 978-1-61779-026-3, Mayer, Bernd (Ed.), Humana Press, March, 2011. [Book chapter].

Safran M, Dalah I, Alexander J, Harel A, Stelzer G, Iny-Stein T, Shmoish M, Rosen N, Bahir I, Madi A, Brewster B, Weisman S, Golan Y and Lancet D. (2010). GeneCards Version 3: the human gene integrator. Database The Journal of Biological Databases and Curation baq020.

Stelzer G, Inger A, Olender T, Iny-Stein T, Dalah I, Harel A, Safran M, Lancet D. (2009). GeneDecks: paralog hunting and gene-set distillation with GeneCards annotation. OMICS a journal of integrative biology 13(6):477-87.

Harel A, Inger I, Strichman-Almashanu L, Safran M, and Lancet, D. (2009). GIFtS: Annotation Landscape Analysis with GeneCards. Bioinformatics. BMC Bioinformatics 10:348.

Erental A, Harel A, and Yarden O. (2007).Type 2A phosphoprotein phosphatase is required for asexual development and pathogenesis of?Sclerotinia sclerotiorum. Mol. Plant-Microbe Interact. 20:944-954.

Harel A, Bercovich S, Yarden, O. (2006). Calcineurin is required for sclerotial development and pathogenicity of Sclerotinia sclerotiorum in an oxalic acid independent manner. Mol. Plant-Microb Interact. 19:682-93.

Harel A, Gorovits R, Yarden O. (2005). Changes in protein kinase A activity accompany sclerotial development in Sclerotinia sclerotiorum. Phytopathology 95: 397-404.

Chen C. Harel A, Gorovoits R, Yarden O, Dickman MB. (2004). MAPK regulation of sclerotial development in Sclerotinia sclerotiorum is linked with pH and cAMP sensing. Mol. Plant-Microb Interact. 17:404-413.





Resistance of tomatoes to Botrytis cinerea.
Databases for Botrytis cinerea.
See all chapters
Updated on: 20/03/18 10:15
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