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שלח באימייל הדפס
Name: Ron Ophir, Ph.D. (Researcher)
Units: Plant SciencesFruit Tree Sciences
Research Interests / Job description  
Tel:  03-9683033 [Office] 03-9683016 [Lab]
Cell: 050-6220003
Email:    ron@agri.gov.il
Office location:Fruit Tree building and Genomics
Address:Institute of Plant Sciences,
Genomics Building, Room 2002, 2nd floor
The Volcani Center ARO,
P.O.Box 6, Bet Dagan 50250, Israel

Principal investigator

Research Interests / Job description
Germplasm collection is the genetic basis for plant breeding and improvement.
We adopt bioinformatics approaches to understand the genetic structure of the germplasm collection. The research methods include genetic markers development, reconciling the cultivars' kinship, reconstructing pan-genome, and applying marker-assisted selection methods.
Further interest in my research studies the genetic determinants of adaptation of crop-wild relatives as a potential genetic reservoir for "lost traits."



Hellwig, T., Abbo, S., Ophir, R., 2021. Drivers of genetic differentiation and recent evolutionary history of an Eurasian wild pea. Journal of Biogeography n/a. https://doi.org/10.1111/jbi.14274

Hellwig, T., Abbo, S., Sherman, A., Ophir, R., 2021. Prospects for the natural distribution of crop wild-relatives with limited adaptability: The case of the wild pea Pisum fulvum. Plant Science 310, 110957. https://doi.org/10.1016/j.plantsci.2021.110957

Hellwig, T., Abbo, S., Sherman, A., Coyne, C.J., Saranga, Y., Lev?Yadun, S., Main, D., Zheng, P., Ophir, R., 2020. Limited divergent adaptation despite a substantial environmental cline in wild pea. Molecular Ecology n/a. https://doi.org/10.1111/mec.15633

Rubinstein, M., Eshed, R., Rozen, A., Zviran, T., Kuhn, D.N., Irihimovitch, V., Sherman, A., Ophir, R., 2019. Genetic diversity of avocado (Persea americana Mill.) germplasm using pooled sequencing. BMC Genomics 20, 379. https://doi.org/10.1186/s12864-019-5672-7

Sharabi-Schwager, M., Or, E., Ophir, R., 2017. ctsGE-clustering subgroups of expression data. Bioinformatics. https://doi.org/10.1093/bioinformatics/btx116

Sharabi-Schwager, M., Rubinstein, M., Ish shalom, M., Eshed, R., Rozen, A., Sherman, A., Cohen, Y., Ophir, R., 2016. Experimental Pipeline for SNP and SSR Discovery and Genotyping Analysis of Mango (Mangifera indica L.). BioProtoc 16, e1910. https://doi.org/10.21769

Sherman, A., Rubinstein, M., Eshed, R., Benita, M., Ish-Shalom, M., Sharabi-Schwager, M., Rozen, A., Saada, D., Cohen, Y., Ophir, R., 2015. Mango (Mangifera indica L.) germplasm diversity based on single nucleotide polymorphisms derived from the transcriptome. BMC Plant Biology 15, 277. https://doi.org/10.1186/s12870-015-0663-6

Rubinstein M, Katzenellenbogen M, Eshed R, Rozen A, Katzir N, Colle M, Yang L, Grumet R, Weng Y, Sherman A, Ophir R. Ultrahigh-Density Linkage Map for Cultivated Cucumber (Cucumis sativus L.) Using a Single-Nucleotide Polymorphism Genotyping Array.PLoS One. 2015 Apr 13;10(4);  doi: 10.1371

Abu-Abied M, Szwerdszarf D, Mordehaev I, Yaniv Y, Levinkron S, Rubinstein M, Riov J, Ophir R, Sadot E.Gene expression profiling in juvenile and mature cuttings of Eucalyptus grandis reveals the importance of microtubule remodeling during adventitious root formation. BMC Genomics. 2014 Sep 30;15:826. doi: 10.1186

Cohen S, Itkin M, Yeselson Y, Tzuri G, Portnoy V, Harel-Baja R, Lev S, Sa'ar U, Davidovitz-Rikanati R, Baranes N, Bar E, Wolf D, Petreikov M, Shen S, Ben-Dor S, Rogachev I, Aharoni A, Ast T, Schuldiner M, Belausov E, Eshed R, Ophir R, Sherman A, Frei B, Neuhaus HE, Xu Y, Fei Z, Giovannoni J, Lewinsohn E, Tadmor Y, Paris HS, Katzir N, Burger Y, Schaffer AA. The PH gene determines fruit acidity and contributes to the evolution of sweet melons. Nat Commun. 2014 Jun 5;5:4026.

Chejanovsky N, Ophir R, Schwager MS, Slabezki Y, Grossman S, Cox-Foster D. Characterization of viral siRNA populations in honey bee colony collapse disorder. Virology. 2014 Apr;454-455:176-83. doi: 10.1016

Abu-Abied M, Szwerdszarf D, Mordehaev I, Levy A, Stelmakh OR, Belausov E, Yaniv Y, Uliel S, Katzenellenbogen M, Riov J, Ophir R, Sadot E. Microarray analysis revealed upregulation of nitrate reductase in juvenile cuttings of Eucalyptus grandis, which correlated with increased nitric oxide production and adventitious root formation. Plant J. 2012 Apr 21. doi: 10.1111

Ophir R. and Sherman A. Self-custom-made SFP arrays for nonmodel organisms. 2012 Methods Mol Biol.  815:39-47.

Ophir R., Eshed R., Harel-Beja R., Tzuri G., Portnoy V., Burger Y., Uliel S., Nurit Katzir  N. and Sherman  A. High-throughput marker discovery in melon using a self-designed oligo microarray. 2010 BMC Genomics , 11:269

Ophir R, Pang X, Halaly T, Venkateswari J, Lavee S, Galbraith D, Or E. Gene-expression profiling of grape bud response to two alternative dormancy-release stimuli expose possible links between impaired mitochondrial activity, hypoxia, ethylene-ABA interplay and cell enlargement. 2009 Plant Mol Biol. 76:1-18

Yishay M, Burdman S, Valverde A, Luzzatto T, Ophir R, Yedidia I. 2008 Differential pathogenicity and genetic diversity among Pectobacterium carotovorum ssp. carotovorum isolates from monocot and dicot hosts support early genomic divergence within this taxon. 10(10):2746-59.Environ Microbiol

Feldmesser E, Olender T, Khen M, Yanai I, Ophir R and Lancet D 2006. Widespread ectopic expression of olfactory receptor genes. BMC Genomics 22:7-121

Ohali A, Avigad S, Zaizov R, Ophir R, Horn-Saban S, Cohen IJ, Meller I, Kollender Y, Issakov J, Yaniv I, 2004.   Prediction of high risk Ewing's sarcoma by gene expression profiling. Oncogene 23:8997-9006.

Ner-Gaon H., Halachmi R., Savaldi-Goldstein S., Rubin E., Ophir R. & Fluhr R., 2004  Intron retention is a major and bona fide phenomenon of alternative splicing in Arabidopsis. Plant J. 39:877-85

Sagi M., Davydov O., Orazova S., Yesbergenova Z., Ophir R., Stratmann JW. and Fluhr R. 2004.  Rboh impinges on wound responsiveness and plant development.  Plant Cell. 16(3):616-28

Yanai I., Graur D., and Ophir R. 2004 Incongruent expression profiles between human and mouse orthologous genes suggest widespread neutral evolution of transcription control. OMICS. 8(1):15-24.

Ophir R., Itoh T., Graur D, and Gojobori T., 1999. A Simple Method for Estimating the Intensity of Selection in Protein-Coding Genes. Mol. Biol. and Evol. 16:49-53

Ben-Dor A., Chor B., Graur D., Ophir R. and Pelleg D. 1998.  Constructing Phylogenies from Quartets: Elucidation of Euthrian Superordinal Relationship.  Journal of Comp. Biol. 5:377-390

Ophir R. and Graur D. 1997. Patterns and Rates of Indel Evolution in Processed Pseudogenes From Human and Murids. GENE 205:191-202

Ophir R and Gershoni J.M., 1995. Biased Random Mutagenesis of Peptides: Determination of Mutation Frequency by Computer Simulation.  Protein Eng. 8:143-146


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