En I עב
People | Site
Hello visitor | Log in
HTML tutorial HTML tutorial HTML tutorial HTML tutorial HTML tutorial HTML tutorial
research_title.jpg research_logo.gif
About Institutes Public Relations Technology Transfer Students\International Information Center (Library) Administration
שלח באימייל הדפס
Name: Andrey Shirak, Ph.D. (Engineer/Technician)
Units: Animal ScienceDepartment of Ruminant Science
Research Interests / Job description  
Tel:  08-9484443
Cell: 054-6018120
Email:  shiraka@volcani.agri.gov.il
Research Interests / Job description
Study of the sex-determination mechanisms in animals
Study of the mechanisms for sex-specific mortality
Development of the high-throughput technologies for genetic study
Study of the reproductive behavior and mating system in fish
Study of the genetic architecture and sexual hierarchy in tilapia populations

1.      Shirak A., Zak T., Dor L Benet-Perlberg A., Weller JI., Ron M., and Seroussi E. (2018) Quantitative trait loci on LGs 9 and 14 affect the reproductive interaction between two Oreochromis species, O. niloticus and O. aureus. Heredity https://doi.org/10.1038/s41437-018-0131-9.

2.      Dor L., Shirak A., Rosenfeld H., Meiri-Ashkenazi I., Rubinstein G., Seroussi E., Weller J.I. and Ron M., (2018). Genetic stock identification of the Flathead grey mullet (Mugil cephalus) in Lake Tiberias based on parent-offspring relationship. Isr. J. Aquaculture

3.      Seroussi E., Rosov A., Shirak A., Lam A., Gootwine E. (2017). Unveiling genomic regions that underlie differences between Afec-Assaf sheep and its parental Awassi breed. Genet Sel Evol. 10:49(1):19.

4.      Perelberg A., Zak T., Naor A., Shirak A. (2017). Development of tilapia broodstocks producing all-male hybrids on a commercial scale (In Hebrew). Fish Bull 2017:65-71.

5.      Shirak A., Seroussi U., Gootwine E., Seroussi E. (2017). Sequence motifs capable of forming DNA stem-loop structures act as a replication diode. FEBS Open Bio. 4:7(7):944-952.

6.      Gootwine E., Abu-Siam M., Obolensky A., Rosov A., Honig H., Nitzan T., Shirak A., Ezra-Elia R., Yamin E., Banin E., Averbukh E., Hauswirth W. W., Ofri R. and E. Seroussi. (2017). Gene Augmentation Therapy for a Missense Substitution in the cGMP-Binding Domain of Ovine CNGA3 Gene Restores Vision in Day-Blind Sheep. Invest Ophthalmol Vis Sci. 1:58(3):1577-1584.

7.      Dor L., Shirak A., Rosenfeld H., Meiri I., Band M.R., Korol A., Yefim R., Seroussi E., and Ron M. (2016). Mapping of the sex determination region of Flathead grey mullet (Mugil cephalus). Animal Genetics 47(6):698-707.

8.      Shirak A., Dor L., Seroussi E., Ron M., Hulata G., Golani D. (2016). DNA Barcoding of Fish Species from the Mediterranean Cost of Israel. Mediterranean Marine Science 17(2):459-466.

9.      Velan A., Hulata G., Ron M., Slosman T., Shirak A., and A. Cnaani. (2015). Association between polymorphism in the Prolactin I promoter and growth of tilapia in saline-water. Aquaculture Reports 1: 5–9.

10.  Yosefi S., Shinder D., Hen G., Shirak A. & E. Serussi (2014). Leptin evolution in Aves. Endocrine Abstracts 35 P750. |

11.  Friedman-Einat M, Cogburn LA, Yosefi S, Hen G, Shinder D, Shirak A, and Seroussi E. (2014). Discovery and Characterization of the First Genuine Avian Leptin Gene in the Rock Dove (Columba livia). Endocrinology. 155: 3376–3384.

12.  Eshel, O., Shirak, A., Dor, L., Band M., Zak T., Markovich-Gordon M., Chalifa-Caspi V., Feldmesser E., Weller J-I., Seroussi E., Hulata G. and M. Ron. (2014). Identification of male-specific amh duplication, sexually differentially expressed genes and microRNAs at early embryonic development of Nile tilapia (Oreochromis niloticus). BMC Genomics, 15: 774.

13.  Dor L., Shirak, A., Gorshkov S., Seroussi E., Ron, M and Hulata, G. (2014). Building a basic genomic map of the White Grouper (Epinephelus aeneus) as function for crossing (In Hebrew). Fisheries and Fishbreeding in Israel 2:1822-1826.

14.  Dor L., Shirak, A., Gorshkov S., Band M.R., Korol A., Ronin Y., Curzon A., Hulata, G., Seroussi E., Ron, M (2014). Construction of a Microsatellites-Based Linkage Map for the White Grouper (Epinephelus aeneus). G3-GENES GENOMES GENETICS 4: 1455-1464.

15.  Lourenco D.A.L., Misztal I., Tsuruta S., Aguilar I., Ezra E., Ron M., Shirak A., and J. I. Weller (2013). Methods for genomic evaluation of a relatively small dairy population and effect of genotyped cow information in multiparity analyses. J. Dairy Sci. 97: 1742-1752.

16.  Seroussi E., Glick G., Shirak A., Ezra E., Zeron Y., Ron M . and J. I. Weller (2013). Maternity validation using sire-only BovineSNP50 BeadChip data. Animal Genetics, 44(6), 754–757.

17.  Dor L., Shirak A., Gorshkov S., Ron M. and Hulata G. (2014). Development of genetic markers for the white grouper (Epinephelus aeneus). Aquaculture 420: 104–110.

18.  Shirak A, Palti Y, Bern O, Kocher T, Gootwine E, Seroussi E, Hulata G, Ron M and R.R. Avtalion (2013). A deleterious effect associated with UNH159 is attenuated in twin embryos of an inbred line of blue tilapia (Oreochromis aureus). J. Fish Biol. 82:42–53

19.  Weller JI., Shirak A. Glick G., Ezra E., Zeron Y. and Ron M. (2012) Calculation of breeding values for Israeli cows. Meshek ha-Bakar vehe-Halav (In Hebrew), 359:65-67.

20.  Weller J. I., Glick G., Shirak A., Ezra E., Zeron Y. and M. Ron (2012). Predictive ability of selected subsets of single nucleotide polymorphisms (SNPs) for moderately sized dairy cattle populations. Proc. of Interbull Meeting 46:7-15.

21.  Eshel O., Shirak A., Weller J.I., Hulata G. and Ron M. (2012). Linkage and physical mapping of sex region on LG23 of Nile tilapia (Oreochromis niloticus). G3: Genes, Genomes, Genetics, 2:35-42.

22.  Ron M., Shirak A. Glick G., Ezra E., Zeron Y. and Weller JI. (2012) Genetic analysis of bulls and cows using DNA arrays for management and breeding. Meshek ha-Bakar vehe-Halav (In Hebrew), 359:68-69.

23.  Shirak A,, Barkai O, Lernau O, Kahanov Y, Seroussi E, Ron M. (2012).Barcoding Analysis of Fish Bones from a Shipwreck found at Dor, Israel. Jsr. J. of Aquaculture, 65:873-878.

24.  Weller J. I., Ron M., Glick G., Shirak A., Zeron Y. and Ezra E. (2012). A Simple method for genomic selection for moderately sized dairy cattle populations. An Int. J. of Animal Bioscience, 6 (2):193-202.

25.  Glick G., Shirak A., Uliel S., Zeron Y., Ezra E., Seroussi E., Ron, M. and Weller J. (2011). Signatures of contemporary selection in the Israeli Holstein dairy cattle. Animal Genetics 43: 45–55.

26.  Shirak A., Reicher S., Uliel S., Mehlman T., Shainskaya A., Ron M. and Seroussi E. (2011). Gender and reproductive activity modulate the composition of serum lipocalins in Nile tilapia (Oreochromis niloticus). Gene 504(1): 22-30.

27.  Ron M., Shirak A. Glick G., Ezra E., Zeron Y. and Weller JI. (2011) Genetic analysis of beef cattle using DNA arrays. Yediot LaBokrim (In Hebrew), 129:20-24.

28.  Seroussi, Y., Shirak, A., Seroussi, E. (2011) SNPmplexViewer--toward a cost-effective traceability system. BMC Res. Notes 4:146.

29.  Golik M, Glick G, Reicher S, Shirak A, Ezra E, Zeron Y, Gootwine E, Ron M, Weller JI, Seroussi E (2011). Differential expression of ruminant ZNF496 variants: Association with quantitative trait loci affecting bovine milk concentration and fertility. J.Dairy Sci, 94 (4):2092-2102.

30.  Eshel, O., Shirak A., Weller J.I., T. Slossman, G. Hulata, A. Cnaani and M. Ron. (2011) Fine-mapping of a locus on linkage group 23 for sex determination in Nile tilapia (Oreochromis niloticus). Animal Genetics, 42 (2): 222-224.   

31.  Glick G., Shirak A., Seroussi E., Zeron Y.,Ezra E., Weller J.I. and M. Ron. (2011). Association between a CNV and QTL for fertility on BTA7 in the Israeli Holstein dairy cattle. G3, 1:65-74.

32.  Mota-Velasco J.C, Ferreira I.A, Cioffi M.B, Ocalewicz K, Campos-Ramos R, Shirak A, Lee B-Y, Martins C, Penman D.J.(2010). Characterisation of the chromosome fusions in Oreochromis karongae. Chromosome Res. 18:575-586.

33.  Seroussi E., Glick G., Shirak A., Yakobson E., Weller J.I., Ron M., Ezra E., Zeron Y. (2010). Analysis of variation of copy losses and gains on Holstein cattle autosomes using BeadChip SNPs, BMC Genomics,11: 673.

34.  Shirak, A., Grabherr, M., Di Palma, F., Lindblad-Toh, K., Hulata, G., Ron, M., Kocher, T.D. and Seroussi, E. (2009). Identification of repetitive elements in the genome of Oreochromis niloticus: Tilapia repeat-masker. Marine Biotechnology, 12(2) 121-125.

35.  Shirak A, Cohen-Zinder M, Barroso RM, Seroussi E, Ron M, Hulata G (2009). DNA barcoding of Israeli endemic and introduced cichlids. Isr. J. Aquacult.-Bamidgeh, 61: 83-88.

36.  Karniol B., Shirak A., Baruch E., Tal A., Cahana A., Kam M., Skalski Y., Singrün C., Brem G., Weller J.I., Ron M., Seroussi E. (2009). Development of a 25-plex SNP assay for traceability in cattle. Animal Genetics, 40(3):353-6.

37.  Shirak A., Golik M., Lee B-Y, Howe A.E., Kocher T.D., Hulata G., Ron M. and Seroussi E. (2008). Copy number variation of lipocalin family genes for male-specific proteins in tilapia and its association with gender. Heredity 101: 405-415.

38.  Shirak A., Seroussi E., Zilberman N., Domokhovsky R., Cnaani A., Kocher T. D., Ron M. and G. Hulata. (2007). Mapping of candidate genes for sex determination in tilapias. In: Vandeputte M., Chatain B. and G. Hulata (eds.), Proc. of the Ninth International Symposium on Genetics in Aquaculture, S271. Aquaculture, 272.

39.  Machnes Z., Avtalion R., Shirak A., Trombka D., Wides R., Fellous M., Don J. (2008). Male-Specific Protein (MSP); A New Gene Linked to Sexual Behavior and Aggressiveness of Tilapia Males. Hormones and Behavior, 54(3):442-9.

40.  Cnaani A, Lee B-Y, Zilberman N, Ozouf-Costaz C, Hulata G, Ron M, D'Hont A, Baroiller J-F, D'Cotta H, Penman DJ, Tomasino E, Coutanceau J-P, Pepey E, Shirak A, Kocher TD, (2008). Genetics of sex determination in tilapiine species. Sexual Development, 2(1):43-54.

41.  Shirak A., Seroussi E., Cnaani A., Zilberman N., Kocher T. D., Hulata G., and Ron M. (2006). Genetic Basis of Sex Determination in Fishes: Searching for Master Key Regulator Genes in the Sex Determination Pathway of Tilapias Isr. J.Aquacult. 58(4):350.

42.  Korol, A., Shirak, A., Cnaani, A. and Hallerman, E.M., (2006). Chapter 11: Detection and analysis of QTLs for economic traits in aquatic species. In: Liu, Z.J. (ed.). Aquaculture Genome Technologies. Blackwell.

43.  Shirak A., Seroussi E., Cnaani A., Howe A E., Domokhovsky R., Zilberman N., Kocher T. D., Hulata G. and M. Ron. (2006) Amh and Dmrta2 Genes Map to Tilapia (Oreochromis spp.) Linkage Group 23 within QTL Regions for Sex Determination. Genetics, 174(3):1573-1581.

44.  Shirak A., Bendersky A., Hulata G., Ron M. and R.R. Avtalion. (2006) Altered Self-Erythrocyte Recognition and Destruction in an Inbred Line of Tilapia (Oreochromis aureus). The Journal of Immunology, 176: 390-394.

45.  Timan, B., Shirak A., R. Segal, Z. Machnes and R.R. Avtalion (2003). Epitopes of tilapia red blood cells: I. Species specific antibodies for the control of tilapia breeding stocks. Isr. J. Aquacult. 54: 5-11.

46.  Shirak A., Palti Y., Cnaani A., Hulata G., and Ron M. and R.R. Avtalion. (2002) Association between genes with deleterious alleles and sex determination in an inbred line of tilapia (Oreochromis aureus). J. of Heredity, 93:270-276.

47.  Palti Y., Shirak A., Hulata G., R.R. Avtalion, and Ron M. (2002) Detection of genes with deleterious alleles in an inbred line of tilapia (Oreochromis aureus). Int. Aquaculture. 206: 151-164.

48.  Shirak A. and Avtalion R.R. (2001) Full-sib mating can reduce deleterious effects associated with residual sperm inheritance in gynogens Isr. J. Aquacult 53: 15-22.

49.  Palti Y., Shirak A., Cnaani A., E.Feldmesser, R.R. Avtalion, Hulata G., and Ron M. (2000) A microsatellite marker harbors a limited number of copies in the genome of two tilapia species (Oreochromis aureus and O.niloticus) Animal Genetics 32: 40-41.

50.  Shirak A., Kuperman Y., and Avtalion R.R. (2000). Body and peritoneum color determination in Tilapia spp. Isr. J. Aquacult. 52, 21-29.

51.  Belotsky S., Tinman S., Shirak A., Bejerano I., Levy R., and R.R. Avtalion. (1998) Spontaneous and stimulated chemiluminescence responses of blood leukocytes from healthy and infected tilapia. Isr. J.Aquacult.50: 67-72.

52.  Shirak A., Vartin J., Don J., and R.R. Avtalion. (1998) Production of viable diploid mitogynogenetic Oreochromis aureus using the cold shock and its optimization through definition of cleavage time. Isr .J.Aquacult. 50: 140-150.

Updated on: 25/10/20 16:00
govi semel
Copyright © 2008, The State of Israel. All Rights Reserved. Terms of use I Contact Us I Jobs I F.A.Q I Site administrator