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שלח באימייל הדפס
Name: Moshe Shemesh, Ph.D. (Researcher)
Units: Postharvest and Food SciencesDepartment of Food Science
Research Interests / Job description  
Tel:  03-9683868 03-9683702 03-9683420
Cell: 050-6220364
Email:    moshesh@agri.gov.il
Office location:Department of Food Science, the building of Soil, Water and Environmental Sciences, Room 106.
Address:Department of Food Science
Agricultural Research Organization The Volcani Center
Derech Hamacabim,POB 15159, Rishon LeZion 7528809, Israel


Research Scientist


Research Interests / Job description
Molecular mechanisms of bacterial adaptation to dairy-associated environments
Bacterial biofilms - colonization onto surfaces and development of complex microbial communities.
Psychrotrophic bacteria and their survival mechanisms
Development of novel antimicrobial approaches
Food associated thermo-acidophilic bacteria
Developing novel means to improve the microbial quality of dairy food
Investigating microbiome of milk and its products
Positive microbiology - probiotics and prebiotics



2010  Postdoc at Harvard University

2008  Ph.D. at The Hebrew University of Jerusalem

2001  M.Sc. at The Hebrew University of Jerusalem

1997  B.Sc. at The Hebrew University of Jerusalem

Recent publications

Hutchings C., Rajasekharan S.K., Reifen R., Shemesh M. (in press). Mitigating milk-associated bacteria through inducing zinc ions antibiofilm activity. Foods.

Duanis-Assaf D., Steinberg D., Shemesh M. (in press). Efficiency of Bacillus subtilis Metabolism of Sugar Alcohols Governs its Probiotic Effect Against Cariogenic Streptococcus mutans. Artif. Cells Nanomed. Biotechnol.

Shemesh M., Ostrov I. (2020). Role of Bacillus species in biofilm persistence and emerging antibiofilm strategies in the dairy industry. J Sci Food Agric. 100(6):2327-2336.

Duanis-Assaf D., Kenan E., Sionov R., Steinberg D., Shemesh M. (2020). Proteolytic Activity of Bacillus subtilis Upon κ-Casein Undermines Its "Caries-Safe" Effect. Microorganisms 8(2):221.

Gingichashvili S, Duanis-Assaf D., Shemesh M., Featherstone J, Feuerstein O, Steinberg D. (2020). The Adaptive Morphology of Bacillus subtilis Biofilms: A Defense Mechanism against Bacterial Starvation. Microorganisms 8(1):62.

Hadaya O., Landau S. Y., Glasser T., Muklada H., Deutch T., Shemesh M., Argov-Argaman N. (2020). Producing pasture-like milk from goats in confinement. Livestock Science 236:104056.

Kimelman H., Shemesh M. (2019). Probiotic Bifunctionality of Bacillus subtilis - Rescuing Lactic Acid Bacteria from Desiccation and Antagonizing Pathogenic Staphylococcus aureus. Microorganisms 7 (10):407.

Demishtein K., Reifen R., Shemesh M. (2019). Antimicrobial Properties of Magnesium Open Opportunities to Develop Healthier Food. Nutrients 11(10), 2363.

Ostrov I., Polishchuk I., Shemesh M. Pokroy B. (2019). Novel Superhydrophobic Wax Coatings for Prevention of Biofilm Establishment in Dairy Food. ACS Applied Bio Materials 2(11), 4932-4940.

Ostrov I. Paz T., Shemesh M. (2019). Robust Biofilm-Forming Bacillus Isolates from the Dairy Environment Demonstrate an Enhanced Resistance to Cleaning-in-Place Procedures. Foods 8:134.

Ostrov I. Sela N., Belausov E., Steinberg D., Shemesh M. (2019). Adaptation of Bacillus Species to Dairy Associated Environment Facilitates their Biofilm Forming Ability. Food Microbiology 82:316-324.

Friedlander A., Nir S., Reches M., Shemesh M. (2019). Preventing Biofilm Formation by Dairy-Associated Bacteria Using Peptide-Coated Surfaces. Front. Microbiol. 10:1405.

Duanis-Assaf D., Duanis-Assaf T., Zeng G., Meyer R.L., Reches M., Steinberg D., Shemesh M. (2018). Cell wall associated protein TasA provides an initial binding component to extracellular polysaccharides in dual-species biofilm. Sci. Rep. 8:9350. 

Yahav S. , Berkovich Z., Ostrov I., Reifen R., Shemesh M. (2018). Encapsulation of beneficial probiotic bacteria in extracellular matrix from biofilm-forming Bacillus subtilis. Artif. Cells Nanomed. Biotechnol. 27:1-9.                                                         

Boguslavsky Y., Shemesh M., Friedlander A., Rutenberg R., Molad-Filossof A., Buslovich A., Poverenov E. (2018). Eliminating the Need for Biocidal Agents in Anti-Biofouling Polymers by Applying Grafted Nanosilica Instead. ACS Omega 3:12437-12445.

Ben Ishay N., Oknin H., Steinberg D., Berkovich Z., Reifen R., Shemesh M. (2017). Enrichment of milk with magnesium provides healthier and safer dairy products. npj Biofilms and Microbiomes. 3:24.

Gingichashvili S., Duanis-Assaf D., Shemesh M., Featherstone J., Feuerstein O., Steinberg D. (2017). Bacillus subtilis Biofilm Development - a Computerized Study of Morphology and Kinetics. Front. Microbiol. 8:2072.

Habib C., Yu Y., Gozzi K., Ching C., Shemesh M., Chai Y. (2017). Characterization of the regulation of a plant polysaccharide utilization operon and its role in biofilm formation in Bacillus subtilis. PLoS One. 12(6):e0179761.

Ostrov I., Harel A., Bernstein S., Steinberg D., Shemesh M. (2016). Development of a method to determine the effectiveness of cleaning agents in removal of biofilm derived spores in milking system. Front. Microbiol. 7:1498.

Duanis-Assaf D. ,Steinberg D., Chai Y. , Shemesh M. (2016).  The LuxS based quorum sensing governs lactose induced biofilm formation by Bacillus subtilis. Front. Microbiol. 6:1517.

Ogiy S., Chen Y., Pasvolsky R., Weinberg Z.G., Shemesh M. (2016). High resolution melt analysis to confirm the establishment of Lactobacillus plantarum and Enterococcus faecium from silage inoculants during ensiling of wheat. Grassl. Sci. 62:23-36.


Oknin H., Steinberg D., Shemesh M. (2015). Magnesium ions mitigate biofilm formation of Bacillus species via downregulation of matrix genes expression. Front. Microbiol. 6:907.

Ostrov I., Sela N., Freed M., Khateb N., Kott-Gutkowski M., Inbar D., Shemesh M.  (2015). Draft Genome Sequence of Bacillus licheniformis S127 Isolated from Sheep Udder Clinical Infection. Genome Announc. 3(5).

Khaskin E., Fadida T., Kroupitski Y., Shemesh M., Cristaldi D.A., Gulino A., Poverenov E. (2015). A contact active bactericidal stainless steel via a sustainable process utilizing electrodeposition and covalent attachment in water. Green Chem. 17:2344-2347.

Pechook S., Sudakov K., Polishchuk I., Ostrov I., Zakin V., Pokroy B., Shemesh M. (2015). Bioinspired passive anti-biofouling surfaces preventing biofilm formation. J. Materials Chem. B. 3:1371-1378.

Assaf D., Steinberg D., Shemesh M. (2015). Lactose triggers biofilm formation by Streptococcus mutans. Int. Dairy J. 42:51-57.

Shemesh M., Pasvolsky R., Zakin V. (2014). External pH is a cue for the behavioral switch that determines surface motility and biofilm formation of Alicyclobacillus acidoterrestris. J. Food Prot. 8:1252-1440.

Pasvolsky R., Zakin V., Ostrova I., Shemesh M. (2014). Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. Int. J. Food Microbiol. 181C:19-27.

Shemesh M., Pasvolsky R., Sela N., Green S.J., Zakin V. (2013) Draft genome sequence of Alicyclobacillus acidoterrestris strain ATCC 49025. Genome Announc. 1(5).

Poverenov E., Shemesh M., Gulino A., Cristaldi D.A., Zakin V., Tatiana Yefremov T., Granit R. (2013). Durable Contact Active Antimicrobial Materials Formed by a One-Step Covalent Modification of Polyvinyl Alcohol, Cellulose and Glass Surfaces. Colloids Surf B Biointerfaces. 112C:356-361.

Shemesh M., Chai Y. (2013) A combination of glycerol and manganese promotes biofilm formation in Bacillus subtilis via the histidine kinase KinD signaling. J. Bacteriol. 195:2747-2754.

The Hebrew University of Jerusalem, The Robert H. Smith Faculty of Agriculture, Food and Environment, Biochemistry and Food Science.
1.Biofilms in the Food Industry

2.Food Microbiology and Sanitation

Lab members

Yulia Kroupitski (Research engineer)

Keren Demishtein (Postdoc)

Bat-chen Cohen (Postdoc)

Satish Kumar Rajasekharan (Postdoc)

Tali Paz (Research engineer)

Chen Raz (Ph.D. student)

Ann-Susan Satish (Ph.D student)

Alexander Andreev (Research engineer)

Vijaya Gupta (Postdoc)

Carolina Szlufman (Intern student)

Vilhemina Yaa amoah (M.Sc. student)

Inbar Shviro (B.Sc. Student)

Former lab members

Solange Bernstein (Technician)

Ronit Pasvolsky (Postdoctoral fellow)

Svetlana Oggie (M.Sc.)

Noa Itamar (B.Sc. student)

Bat-El Dukarker (B.Sc. student)

Varda Zakin (Technician)

Dana Inbar (M.Sc.)

Hilla Ben-Amy (B.Sc. student)

Noa Ben-Ishay (M.Sc.)

Sagit Yahav (M.Sc.)

Ronen Bustan (M.Sc.)

Or Haim (B.Sc. student)

Yulia Gololobova (Technician)

Ygal Achmon (Postdoc)

Yael Hanoch (M.Sc.)

Ievgeniia Ostrov (Ph.D.)

Alon Friedlander (M.Sc.)

Danielle Assaf (Ph.D.)

Hadar Kimelman (M.Sc.)

Carmel Hutchings (M.Sc.)

Updated on: 06/08/20 18:27
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