Affecting early life poultry development to improve domestic fowl livestock
Epigenetics: mechanism of environmental influence on gene expression
Expression pattern of the H3K27-specific methyltransferase, EZH2, in the PO/AH of 3-day-old chicks
Colocalization of EZH2 and H3K27me2 in PO/AH cells by double immunohistochemical staining. Representative pictures of the same field of the PO/AH of 12-h heat-treated chicks. The brain section was photographed at 200X magnification under different filters, enabling the visualization of fluorescent signals from FITC (upper left panel), Cy3 (upper right panel) and DAPI (lower right panel). The merging of H3K27me2 and EZH2 pictures (lower left panel)
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Meiri, N. (2008) 14-3-3ε expression is induced during the critical period of thermal control establishment. Developmental Neurobiology 68:62-72.
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Marco, A., Kisliouk, T., Weller, A. and Meiri, N. (2013) High fat diet induces hypermethylation of the hypothalamic Pomc promoter and obesity in post-weaning rats. Psychoneuroendocrinology 38:2844-2853.
Marco, A., Kisliouk, Ts., Tabechnik, Ts., Meiri, N and Weller, A. (2014) Overweight and CpG methylation of the Pomc promoter in offspring of high-fat-diet-fed dams are not “reprogrammed” by regular chow diet in rats FASEB J. (fj.14-255620. Published online July 23, 2014)
Kisliouk, T Cramer T. and Meiri, N. (2014) heat stress attenuates new cell generation in the hypothalamus: a role for mir-138. Neuroscience 277: 624-636