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STATE OF ISRAEL I MINISTRY OF AGRICULTURE AND RURAL DEVELOPMENT   
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About Institutes Public Relations Technology Transfer Students\International Library Administration
שלח באימייל הדפס
 
Name: Eyal Seroussi, Ph.D. (Researcher)
Units: Animal ScienceDepartment of Ruminant Science
Research Interests / Job description  
Tel:  08-9484425
Fax:08-9470587
Email:    seroussi@agri.huji.ac.il
Address:Department of Quantitative and Molecular Genetics
Institute of Animal Science
Agricultural Research Organization,
The Volcani Center,
HaMaccabim Road, Rishon LeTsiyon, P.O.B 15159, 7528809, Israel

Researcher

Research Interests / Job description
Animal genomics, genetics and bioinformatics.

Research Interests

Publications (past 10 years)

Ron, M., Israeli, G., Seroussi, E., Weller, J.I., Gregg, J.P., Shani, M.,  Medrano J.F. (2007) Combining mouse mammary gland gene expression and comparative mapping for the identification of candidate genes for QTL of milk production traits in cattle. BMC Genomics 8:183.

Seroussi, Y., Seroussi, E. (2007) TraceHaplotyper: Using direct sequencing to determine the phase of an indel followed by biallelic SNPs. BioTechniques 43:452-456.

Weller, J.I., Golik, M., Reikhav, S., Domochovsky, R., Seroussi, E. Ron M. (2008) Detection and Analysis of QTL Affecting Production and Secondary Traits on Chromosome 7 in Israeli Holsteins. J. Dairy Sci. 91:840-846.

Weller, J.I., Golik, M., Seroussi, E., Ron, M. Ezra, E. (2008) Detection of quantitative trait loci affecting twinning rate in Israeli Holsteins by the daughter design. J Dairy Sci. 91:2469-2474.

Shirak, A., Golik, M., Lee, B.Y., Howe, A.E., Kocher, T.D., Hulata, G., Ron, M., Seroussi, E. (2008) Copy number variation of lipocalin family genes for male-specific proteins in tilapia and its association with gender. Heredity. 101:405-415.

Seroussi, E. (2009) Concordance test emerges as a powerful tool for identifying quantitative trait nucleotides: lessons from BTA6 milk yield QTL. Anim. Genet. 40:230-234.

Karniol, B., Shirak A., Baruch, E., Singrün, C., Tal, A., Cahana, A., Kam, M., Skalski ,Y., Brem, G., Weller, J.I., Ron, M., Seroussi, E. (2009) Development of a 25-plex SNP assay for traceability in cattle. Anim. Genet. 40:353-356.

Shirak, A., Cohen-Zinder, M., Melon, R., Seroussi E., Ron, M. Hulata, G. (2009) DNA barcoding of Israeli endemic and introduced cichlids. Israeli J. Aquaculture 62:83-88.

Shirak, A., Grabherr, M., Di Palma, F., Lindblad-Toh, K., Hulata, G., Ron, M., Kocher, TD., Seroussi, E. (2009) Identification of Repetitive Elements in the Genome of Oreochromis niloticus: Tilapia Repeat Masker. Mar. Biotechnol. (NY) 12:121-125.

Reicher, S., Seroussi, E., Gootwine, E. (2010) A mutation in gene CNGA3 is associated with day blindness in sheep. Genomics 95:101-104.

Weller, J.I., Glick, G., Ezra, E., Zeron, Y., Seroussi E., Ron, M. (2010) Paternity validation and estimation of genotyping error rate for the BovineSNP50 BeadChip. Anim. Genet. 41:551-553.

Seroussi, E., Yakobson, E. (2010) Bovine mtDNA D-loop haplotypes exceed mutations in number despite reduced recombination: an effective alternative for identity control. Animal 4: 1818-1822.

Seroussi, E., Giora, G., Shirak, A., Yakobson, E., Weller, J.I., Ezra, E., Zeron (2010) Analysis of copy loss and gain variations in Holstein cattle autosomes using BeadChip SNPs. BMC Genomics 11:673.

Golik, M., Glick, G., Reicher, S., Shirak, A., Ezra, E., Zeron, Y., Gootwine, E., Ron, M., Weller, J.I., Seroussi E. (2011) Differential expression of ruminant ZNF496 variants: Association with QTL affecting bovine milk concentration and fertility. J. Dairy Sci. 94:2092-2102.

Reicher, S., Gertler, A., Seroussi, E., Shpilman, M., Gootwine, E. (2011) Biochemical and in-vitro biological significance of natural sequence variation in the ovine leptin gene. Gen. Comp. Endocrinol. 173:63-71.

Seroussi, Y., Shirak, A., Seroussi, E. (2011) SNPmplexViewer--toward a cost-effective traceability system. BMC Res. Notes 4:146.

Glick, G., Shirak, A., Seroussi, E., Zeron, Y., Ezra E., Weller, J.I . Ron, M. (2011) Fine mapping of a QTL for fertility on BTA7 and its association with a CNV in the Israeli Holsteins. G3 1:65-74.

Seroussi, E., Yakobson, E., Garazi, S., Oved, Z. Halachmi I. (2011) Long-term survival of flag ear-tags on an Israeli dairy farm. J. Dairy Sci. 94:5533-5.

Reicher, S., Seroussi, E., Weller, J.I., Rosov, A., Gootwine, E. (2012) Ovine mitochondrial DNA sequence variation and its association with production and reproduction traits within an Afec-Assaf flock. J. Anim. Sci. 90:2084-91.

Glick, G., Shirak, A., Uliel, S., Zeron, Y., Ezra, E., Seroussi, E., Ron, M., Weller, J.I. (2012) Signatures of contemporary selection in the Israeli Holstein dairy cattle. Anim. Genet. 43 Suppl 1:45-55.

Shirak, A., Reicher, S., Uliel, S., Mehlman, T., Shainskaya, A., Ron, M., Seroussi, E. (2012) Gender and sexual behavior modulate the composition of serum lipocalins in Nile tilapia (Oreochromis niloticus). Gene 504:22-30.

Shirak, A., Palti, Y., Bern, O., Kocher, T. D., Gootwine, E., Seroussi, E., Hulata, G., Ron, M., Avtalion, R. R. (2013) A deleterious effect associated with UNH159 is attenuated in twin embryos of an inbred line of blue tilapia Oreochromis aureus J. Fish Biol. 82:42-53.

Shirak, A., Barkai, O., Lernau, O., Kahanov, Y., Seroussi, E., Ron, M. (2013) DNA barcoding analysis of fish bones from a shipwreck found at Dor, Israel.  Israeli J. Aquaculture-Bamidgeh 65: 873.

Seroussi, E., Glick, G., Shirak, A., Ezra, E., Zeron, Y., Ron, M., Weller, J.I. (2013) Maternity validation using sire-only BovineSNP50 BeadChip data. Anim. Genet. 44:754-757.

Gertler, A., Shinder, D., Yosefi, S., Shpilman, M., Rosenblum, C.I., Ruzal, M., Seroussi, E., Friedman-Einat, M. (2013) Pegylated leptin antagonist with strong orexigenic activity in mice is not effective in chickens. J. Exper. Biol. 217: 180-184.

Seroussi, E., Klompus, S., Silanikove, M., Krifucks, O., Shapiro, F., Gertler, A., Leitner, G. (2013) Non-bactericidal secreted phospholipase A2s are potential anti-inflammatory factors in the mammary gland. Immunogenetics 65: 861-871.

Weller, J.I, Glick, G., Shirak, A., Ezra, E., Seroussi, E., Shemesh, M., Zeron, Y., Ron, M. (2013) Predictive ability of selected subsets of single nucleotide polymorphisms (SNPs) in a moderately sized dairy cattle population. Animal 8: 208-216.

Friedman-Einat, M., Cogburn, L. A., Yosefi, S., Hen, G., Shinder, D., Shirak A., Seroussi, E. (2014) Discovery and characterization of the first genuine avian leptin gene in the rock dove (Columba livia). Endocrinology 155: 3376-3384.

Dor, L., Shirak, A., Gorshkov, S., Band, M. R., Korol, A., Ronin, Y., Curzon, A., Hulata, G., Seroussi, E., Ron, M. (2014) Construction of a microsatellites-based linkage map for the White Grouper (Epinephelus aeneus). G3 4:1455-1464.

Friedman-Einat, Seroussi, E. (2014) Quack leptin. BMC genomics 15:551.

Eshel, O., Shirak, A., Dor, L., Band, M., Zak, T., Markovich-Gordon, M., Chalifa-Caspi, V., Feldmesser, E., Weller, J. I., Seroussi, E., Hulata, G. and Ron, M. (2014) Identification of male-specific amh duplication, sexually differentially expressed genes and microRNAs at early embryonic development of Nile tilapia (Oreochromis niloticus) BMC Genomics 15:774.

Ronkin, D., Seroussi, E., Nitzan, T., Doron-Faigenboim, A. and Cnaani, A. (2015) Intestinal transcriptome analysis revealed differential salinity adaptation between two tilapiine species. Comp. Biochem. Physiol. Part D Genomics Proteomics 13:35-43.

Seroussi, E., Cinnamon, Y., Yosefi, S., Genin, O., Gage-Smith, J., Rafati, N., Bornelöv, S., Andersson, L. and Friedman-Einat, M. (2015) Identification of the long-sought leptin in chicken and duck: expression pattern of the highly GC-rich avian leptin fits an autocrine/paracrine rather than endocrine function. Endocrinology 157:737-751.

Shirak, A., Dor, L., Seroussi, E., Ron, M., Hulata, G. and Golani, D. (2015). DNA barcoding of fish species from the Mediterranean coast of Israel. Mediterranean Mar. Sci. 17: 2.

Dor L., Shirak A., Rosenfeld H., Ashkenazi I.M., Band M.R., Korol A., Ronin Y., Seroussi, E., Weller, J.I. and Ron, M. (2016). Identification of the sex-determining region in flathead grey mullet (Mugil cephalus). Anim. Genet. 47:698-707.

Seroussi, E., Rosov, A., Shirak, A., Lam, A. and Gootwine, E. (2017). Unveiling genomic regions that underlie differences between Afec-Assaf sheep and its parental Awassi breed. Genet Sel Evol. 49:19.

Gootwine, E., Abu-Siam, M., Obolensky, A., Rosov, A., Honig, H., Nitzan, T., Shirak, A., Ezra-Elia, R., Yamin, E., Banin, E., Averbukh, E., Hauswirth, W.W., Ofri, R., and Seroussi, E. (2017). Gene augmentation therapy for a missense substitution in the cGMP-binding domain of ovine CNGA3 gene restores vision in day-blind sheep. Invest. Ophthalmol. Vis. Sci. 58:1577-1584.

Shirak, A., Seroussi, U., Gootwine, E. and Seroussi, E. (2017). Sequence motifs capable of forming DNA stem-loop structures act as a replication diode. FEBS Open Bio. 7:944-952

Bornelöv, S., Seroussi, E., Yosefi, S., Pendavis, K., Burgess, S.C., Grabherr, M., Friedman-Einat, M., and Andersson, L. (2017) Identification of chicken genes previously assumed to be evolutionarily lost. Genome Biol. 18:112.

Seroussi, E., Pitel, F., Leroux, S., Morisson, M., Bornelöv, S., Miyara, S., Yosefi, S., Cogburn, L.A., Burt, D.W., Andersson, L. and Friedman-Einat, M. (2017) Mapping of leptin and its syntenic genes to chicken chromosome 1p. BMC Genetics 18:77.

Sasson, G., Kruger Ben-Shabat, S., Seroussi, E., Doron-Faigenboim, A., Shterzer, N., Yaacoby, S., Berg Miller, M.E., White, B.A., Halperin, E. and Mizrahi, I. (2017) Heritable Bovine Rumen Bacteria are phylogenetically related and correlated with the cow's capacity to harvest energy form its feed. mBio 8:e00703-17

 

 Current Projects

  • Genes affecting economic traits of dairy cattle, sheep and chicken.
  • Linkage disequilibrium mapping of QTLs and pedigree based haplotype reconstruction.
  • Applying machine learning to the prediction of breeding values for quantitative traits using genetic markers.
  • Traceability.
  • Copy number variation in cattle and fish.

 

Updated on: 15/08/17 18:07
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